Microbiota and the Gut-Brain Axis in Health and Disease

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The gut and the brain are two separate, but connected, organs.  When the gut is dysfunctional, due to microbiota imbalance, it has been shown to manifest as a neurological disorder.  Equally, within hours of a traumatic brain injury, the gut is inflamed.  When the gut in inflamed, the intestinal barrier breaks allowing for the translocation of microbial antigens into the bloodstream.  In response to the microbial or dietary antigens, the immune system produces autoreactive antibodies, which can infiltrate the broken blood-brain barrier and trigger neuroautoimmunity.  The dysfunction of the blood-brain barrier and nervous system fuels the gut dysfunction, which fuels the brain dysfunction.  This cyclic phenomenon can lead to neurodegeneration, such as Alzheimer’s disease, cognitive decline and depression.  Therefore, any treatment, or prevention, of neuroautoimmunity, must include a thorough examination of gut function.  Clinical assessments for intestinal barrier and blood-brain barrier, systemic bacterial toxins, predictive antibodies for neuroautoimmunity and treatment protocols for healing barriers and eliminating gut dysbiosis, will be discussed.  Devastating disorders involving neurodegeneration are preventable.

Learning Objectives:

By the end of this presentation the attendee should understand:

  • How to assess both the gut and the brain for better management of chronic neurological disorders.
  •  Expertly assess intestinal and blood-brain barrier dysfunctions.
  • Use predictive antibodies for the identification of neuronal tissue damage caused environmental triggers.
  • Identify modern lifestyles and environmental triggers that are affecting the gut-brain axis and contributing to the neuroautoimmune epidemic.
  • How to repair essential barriers when they are broken.
  • Ways to keep essential barriers functioning throughout one’s lifetime for healthier living.