Genes, Microbes, & Metagenes: Irritable Bowel Syndrome (IBS) Through the Lens of Systems Biology
Robert Rountree, MD
For many years, mainstream textbooks typically characterized irritable bowel syndrome (IBS) as a psychosomatic disorder with a strong emotional component. Sophisticated molecular diagnostic techniques combined with genomic analysis have now shown that IBS is not a simple “functional” disorder. Rather, it is a multifactorial condition with several prominent overlapping subtypes, including dysbiotic, inflammatory, postinfectious, and neurochemical subtypes. This presentation will use the lens of system biology as way to tie together all these seemingly disparate elements into a cohesive diagnostic and treatment strategy when within scope and know when to refer when out of scope.
This presentation was recorded at the 2022 Integrative Healthcare Symposium Annual Conference.