NIH Scientists Visualize Structures of Brain Receptors Using Subcellular Imaging

Scientists at the National Institutes of Health have created high-resolution images of the glutamate receptor, a protein that plays a key role in nerve signaling. The advance, published online in the journal Nature on August 3, 2014, opens a new window to study protein interactions in cell membranes in exquisite detail.

All cells have protein-based receptors on their surface, which act as specific docking sites for key chemicals that trigger a cellular reaction. Defects in…