Study finds gut microbiome related to cardiovascular fitness
Cardiovascular fitness may determine the health of the gut microbiome, according to a new study published in the latest issue of the International Journal of Sport Nutrition and Exercise Metabolism.
The study, conducted by researchers at the San Francisco State University, recruited 20 men and 17 women, mostly from the SF State campus, and tested their cardiovascular fitness on a treadmill. Researchers assessed their body composition in the lab's BOD POD, an air displacement chamber that determines a person's fat and fat-free mass. Participants kept food logs for seven days and provided stool samples at the end of the week.
The university’s Health Equity Research (HER) Lab then extracted DNA to analyze the bacteria composition in the samples. The researchers were investigating the ratio of bacteria called firmicutes to another group, bacteroides, which can be used to gauge overall gut health and composition.
Analysis showed that participants with the best cardiovascular fitness had a higher firmicutes to bacteroides ratio. While most gut bacteria can be beneficial, even bacteroides in some cases, firmicutes bacteria are associated with metabolic byproducts that help prevent bacteria in the gut from leaking into the body.
"These metabolic byproducts help strengthen the intestinal lining and help prevent leaky gut syndrome," said Ryan Durk, who led the study. He says this research reinforces the idea of "exercise as medicine."
"When we say that phrase, we think of it as meaning that exercise will help people stay healthier and live longer, but you don't think about your gut bacteria," Durk said. "We now know that exercise is crucial for increasing beneficial bacteria in the gut."
According to Durk, findings from this study and other studies about the gut microbiome could eventually be used to create individual exercise prescriptions to improve gut and overall health.
"We're not there yet," he said, "but this helps create that foundation."