A 52 yr. old female diagnosed with Lyme disease 4 years ago, treated with long-term antibiotics. Received another tick-bite 8 months ago, now has new-onset night sweats. Her MD recommended Artemisinin for Babesia infection, now has diarrhea associated with use of Artemisinin. A 52 yr. old female diagnosed with Lyme disease 4 years ago, treated with long-term antibiotics. Received another tick-bite 8 months ago, now has new-onset night sweats. Her MD recommended Artemisinin for Babesia infection, now has diarrhea associated with use of Artemisinin.This patient was diagnosed with Lyme disease about 4 years ago, with the initial infection occurring about 35 years before diagnosis. Before the Lyme diagnosis, patient was diagnosed with FMS, CFS, hypothyroid, ADD, GERD, IBS. After 18 months of antibiotics, Bartonella was also identified as causing some of these symptoms. 8 months ago, the patient experienced another tick bite, followed by severe abdominal pain and the onset of night sweats. Hormone levels show patient is still premenopausal. Patient has continued with antibiotics specific for Lyme and Bartonella and recently started on Artemisinin for Babesia.52FemaleRecurrent night sweats, sometimes occur during day. Hormonal levels show premenopausal levels. Fatigue, muscle and joint pain, cognitive difficulties and GI disturbances – GERD, IBS, abd. pain, food intolerances Patient has been on antibiotics and probiotics for the past 4 years. GI problems were minimal before the recent tick bite. After the tick bite, main GI problems were pain and increased heartburn. Multiple GI studies have repeated shown dilation of the Common Bile Duct with no evidence of stones, sludge or tumors. Patient reported history of frequent loose stools but denied diarrhea until after Artemisinin was started. Insurance has denied coverage for Meprone or Malorone for treatment of Babesia. Artemesia was tried but only increased the sweats to occur every 90 minutes. Artemisinin stops the night sweats but causes diarrhea with up to 20 watery stools/day. Additional probiotics have not been helpful in controlling the diarrhea. When the Artemisinin is stopped, the night sweats return, causing disrupted sleep and decreased cognitive function. Charcoal was attempted as a method of absorbing toxins released by the Artemisinin, but it was only partially helpful.What can be done to lessen the side effects of Artemisinin, especially diarrhea?